PRI-002 (the Alzheimer drug candidate) has productively finished Phase I of clinical study comprising healthy volunteers. When administered every day over a course of 4 Weeks, the active material established to be secure for employment in humans. The upcoming milestone will be the evidence of efficacy in people particles in clinical Phase II.

“In last summer, PRI-002 already established its tolerability and safety profile in people when studied as a single dose—up to the utmost projected dosage. The drug levels in the blood surpassed the values that had earlier been therapeutically effectual in animals. Now we were also capable of demonstrating the security of the compound post 4 Weeks of everyday administration,” claims Director of the Institute of Physical Biology and of Jülich’s Structural Biochemistry Institute at Heinrich Heine University Düsseldorf, Prof. Dieter Willbold, to the media in an interview.

The research was performed at the Department of Clinical Pharmacology by Prof. Michael Wolzt at the Medical University of Vienna, in close association with ICS-6’s Dr. Dagmar Jürgens.

On a related note, a new research posted this week in the journal Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, has discovered that a specific class of molecules might assist with detecting Alzheimer’s Disease.

The team of scientists from King’s College London discovered that the amount of the fatty molecules that persuade sleep in blood were much more in those people in the research with amyloid present in the brain, the peptide employed to detect Alzheimer’s Disease.

The amyloid peptide goes to make plaques in the brain that are poisonous to nerve cells. Plaque buildup is believed to begin many years earlier than the appearance of signs such as memory loss. Medicines that have been designed so far to aim at amyloid have not been victorious in reinstating memory.